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[Activation of human natural killer cells by receptor-bound immunoglobulin G]
J Schubert1, W Kolanus, P Delany
1Zentrum Innere Medizin und Dermatologie, Medizinischen Hochschule, Hannover.
Fc receptor-bound human immunoglobulin G can be detected in vitro and in vivo on CD16+ natural killer cells. Cross-linking of CD16-bound IgG via monoclonal antibody results in increased cytotoxic activity of effector cells.
Fc receptor-bound human immunoglobulin G can be detected in vitro and in vivo on CD16+ natural killer cells. Cross-linking of CD16-bound IgG via monoclonal antibody results in increased cytotoxic activity of effector cells.