Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stress, depression, and the immune system.

M Stein1

  • 1Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029-6574.

The Journal of Clinical Psychiatry
|May 1, 1989
PubMed
Summary

Stress impacts neurobiology and immunity, offering insights into depression. While stress affects immunity through complex mechanisms, immune changes are not a universal marker for major depressive disorder, potentially appearing in specific patient subgroups.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MHC-class I antigen expression on micrometastases in bone marrow of patients with head and neck squamous cell cancer.

Anticancer research·2003
Same author

Total skin electron irradiation in mycosis fungoides: comparison between a modified Christie Hospital translational technique and the Stanford technique.

Leukemia & lymphoma·2003
Same author

Factors affecting participation in a child development programme.

International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation·2002
Same author

[Follow-up in patients with head and neck tumors: evaluation of CT criteria for local tumor recurrence].

Laryngo- rhino- otologie·2001
Same author

[Interesting case no. 47. Gout tophus of the vocal cord].

Laryngo- rhino- otologie·2001
Same author

Use of mental health and substance abuse treatment services among adults with HIV in the United States.

Archives of general psychiatry·2001

Area of Science:

  • Neurobiology
  • Immunology
  • Psychiatry

Background:

  • Major depressive disorder is linked to neurobiologic stress processes.
  • Understanding stress's impact on the immune system may clarify depressive disorder biology.

Purpose of the Study:

  • To investigate the complex relationship between stress, neurobiology, and the immune system in the context of depression.

Main Methods:

  • Review and synthesis of studies examining stress-induced alterations in the immune system.
  • Analysis of neurobiologic mechanisms underlying these immune changes.

Main Results:

  • Stress-induced immune modulation is complex, involving diverse neurobiologic pathways.
  • Altered immune measures are not a universal correlate of major depressive disorder.

Conclusions:

  • Immune system alterations may be present in specific subgroups of depressed patients, not all.
  • Further research into neuroimmune interactions is crucial for understanding depression subtypes.

Related Experiment Videos