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Updated: Mar 30, 2026

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
Published on: January 12, 2020
[Progress in studies on the relationship between Dicer and ovarian tumor]
Hua Zhao1, Huajiang Shao2, Jianting Ma2
1Medical School of Ningbo University, Ningbo Zhejiang 315000, China.
Abstract:
MiRNAs are short, noncoding RNAs that modulate gene expression at the posttranscriptional level and induce the degradation of the mRNA transcript or the inhibition of protein translation. Dicer is an endoribonuclease in the RNase III family that is essential for the production of miRNAs. The abnormal expression of Dicer is frequently found in the occurrence and development process of many kinds of tumors, which is closely related to the treatment and prognosis of tumor.

