Optimal Placement of Irradiation Sources in the Planning of Radiotherapy: Mathematical Models and Methods of Solving
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Oleg Blyuss1, Larysa Koriashkina2, Elena Kiseleva3
1Institute for Women's Health, University College London, London WC1E 6BT, UK.
Computational and Mathematical Methods in Medicine
|November 7, 2015
Abstract:
This paper proposes and analyses a mathematical model for the problem of distribution of a finite number of irradiation sources during radiotherapy in continuous environments to maximize the minimal cumulative effects. A new algorithm based on nondifferentiable optimization techniques has been developed to solve this problem.

