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Hepatic and biliary tract abnormalities in patients with AIDS. Sonographic-pathologic correlation
K Grumbach1, B G Coleman, A A Gal
1Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.
Summary
Hepatobiliary ultrasound effectively identifies liver and gallbladder abnormalities in patients with acquired immunodeficiency syndrome (AIDS). This imaging tool aids in diagnosing conditions like fatty liver and infections, guiding further patient care.
Area of Science:
- Radiology
- Hepatology
- Infectious Diseases
Background:
- Acquired immunodeficiency syndrome (AIDS) can lead to significant hepatobiliary complications.
- Early detection of these complications is crucial for managing patients with AIDS.
Purpose of the Study:
- To evaluate the utility of hepatobiliary sonography in patients with AIDS.
- To correlate ultrasound findings with pathological results and literature for etiological insights.
Main Methods:
- Retrospective analysis of hepatobiliary sonograms from 22 AIDS patients.
- Correlation of sonographic abnormalities with pathological findings in 10 patients.
Main Results:
- Common findings included hyperechoic liver parenchyma (45.5%), hepatomegaly (41%), and gallbladder wall thickening (55%).
- Pathological correlations identified hepatic steatosis and granulomatous hepatitis. Biliary abnormalities were linked to infections like cytomegalovirus and cryptosporidiosis.
Conclusions:
- Hepatobiliary ultrasound is an effective screening tool for AIDS patients with hepatobiliary dysfunction.
- Sonography aids in directing further diagnostic and therapeutic interventions.