Noninvasive Testing in Emergency Department Patients with Low-Risk Chest Pain: Does the Evidence Support Current

Andrew J Foy1, Christopher Sciamanna, William R Davidson

  • 1From the *Division of Cardiology, Heart and Vascular Institute, †Department of Public Health Sciences, Hershey, PA, and ‡Department of Medicine, Penn State Hershey Medical Center, Hershey, PA.

Cardiology in Review
|November 7, 2015
PubMed

Insights

Patients with chest pain and no heart attack signs have very low risk. Noninvasive cardiac testing is recommended, but its benefits versus risks for these patients require careful consideration.

Area of Science:

  • Cardiology
  • Emergency Medicine
  • Diagnostic Testing

Background:

  • Patients presenting to emergency departments with chest pain often undergo evaluation for acute coronary syndromes.
  • Electrocardiogram (ECG) and cardiac markers are initial diagnostic tools.
  • Current guidelines recommend noninvasive cardiac testing (IIa) for low-risk patients with no ischemic evidence.

Purpose of the Study:

  • To evaluate the benefits versus risks of noninvasive cardiac testing in patients with chest pain but no ischemic evidence.
  • To review existing literature supporting current guidelines and contemporary observational studies.
  • To address the clinical utility of further cardiac testing in a very low-risk population.

Main Methods:

  • Systematic review of literature cited in American Heart Association/American College of Cardiology guidelines.
  • Inclusion of large, contemporary, comparative observational studies not previously cited.
  • Analysis focused on risk stratification and diagnostic yield in low-risk chest pain patients.

Main Results:

  • Patients with normal ECG and negative cardiac markers are at very low risk for acute coronary syndromes.
  • The IIa recommendation for noninvasive testing in this group is based on selected literature.
  • Contemporary studies provide further data on the risk-benefit profile of testing.

Conclusions:

  • The decision to pursue noninvasive cardiac testing in low-risk chest pain patients requires careful consideration of potential benefits against associated risks.
  • Further research may refine recommendations for this specific patient cohort.
  • Optimizing diagnostic strategies is crucial for efficient emergency department resource utilization.

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