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Updated: Aug 11, 2026

Simultaneous Measurements of Intracellular Calcium and Membrane Potential in Freshly Isolated and Intact Mouse Cerebral Endothelium
09:45

Simultaneous Measurements of Intracellular Calcium and Membrane Potential in Freshly Isolated and Intact Mouse Cerebral Endothelium

Published on: January 20, 2019

[Blood cells and their sensitivity to calcium antagonists in patients with cerebrovascular disorders]

S E Akopov, G R Martirosian, Iu S Tunian

    Klinicheskaia Meditsina
    |January 1, 1989
    PubMed

    Patients with ischemic-type cerebral dyshematopoiesis have disturbances of blood cell function (their enhanced aggregation and reduction of leucocyte and erythrocyte deformation). Calcium antagonist nifedipine can neutralize these disturbances but it reduces blood cell sensitivity to it. The effectiveness of nifedipine can be increased by giving it in combination with prostacyclin. Blood cell sensitivity to this combination of agents changes insignificantly. It is recommended that nifedipine and medicinal agents which increase blood prostacyclin concentration be used in combination.

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