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Complications of Varicella in Unvaccinated Children From Romania, 2002-2013: A Retrospective Study

Corneliu Petru Popescu1, Emanoil Ceausu, Simin Aysel Florescu

  • 1From the *Carol Davila University of Medicine and Pharmacy; †Dr Victor Babes Clinical Hospital of Infectious and Tropical Diseases; and ‡Stefan S. Nicolau Institute of Virology, Bucharest, Romania.

The Pediatric Infectious Disease Journal
|November 7, 2015
PubMed

Insights

Varicella (chickenpox) hospitalizations in Romania were highest in infants under 1 year old. Younger age and later diagnosis independently predicted severe varicella complications, affecting half of all hospitalized patients.

Area of Science:

  • Epidemiology
  • Clinical Medicine
  • Public Health

Background:

  • Varicella (chickenpox) is a common infectious disease, but complications can lead to hospitalization.
  • Understanding hospitalization patterns is crucial for public health interventions and resource allocation.

Purpose of the Study:

  • To analyze the epidemiologic and clinical characteristics of varicella-related hospitalizations in Romania between 2002 and 2013.
  • To identify predictors of varicella-related complications in hospitalized patients.

Main Methods:

  • Retrospective analysis of national hospitalization data from 2002-2013.
  • Statistical analysis to determine hospitalization rates and identify independent predictors of complications.

Main Results:

  • The highest varicella hospitalization rate was observed in the 0-1 year age group.
  • Younger age was a significant independent predictor of varicella-related complications.
  • Diagnosis after 2007 was also an independent predictor of complications.
  • Varicella-related complications were recorded in approximately 50% of all hospitalized cases.

Conclusions:

  • Infants aged 0-1 year represent the most vulnerable group for varicella hospitalizations in Romania.
  • Timely diagnosis and intervention are critical, as younger age and later diagnosis are linked to increased complication risk.
  • Public health strategies should focus on this high-risk group to mitigate severe varicella outcomes.

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