Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Equilibrium and Balance01:15

Equilibrium and Balance

8.0K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
8.0K
The Vestibular System01:29

The Vestibular System

45.1K
The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
45.1K
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

1.0K
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
1.0K
Disorder of Water Balance01:29

Disorder of Water Balance

2.8K
Water balance disorders are medical conditions that occur when there is a deviation from the body's water volume or osmolarity, disrupting normal homeostasis and leading todehydration, hypotonic hydration, hyperhydration, edema, or water intoxication.
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
2.8K
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

1.1K
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
1.1K
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

1.3K
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ear wax.

BMJ (Clinical research ed.)·2015
Same author

Ear wax.

BMJ clinical evidence·2015
Same author

Middle-ear pain and trauma during air travel.

BMJ clinical evidence·2015
Same author

The concept lens diagram: a new mechanism for presenting biochemistry content in terms of "big ideas".

Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology·2011
Same author

Diagnose and treat hearing loss.

The Practitioner·2006
Same author

Cervical endplay assessment does not improve the efficacy of cervical manipulation.

The Australian journal of physiotherapy·2004

Related Experiment Video

Updated: Mar 30, 2026

Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease
04:11

Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease

Published on: April 28, 2023

2.8K

Menière's disease.

Tony Wright1

  • 1UCL Ear Institute, London, UK.

BMJ Clinical Evidence
|November 7, 2015
PubMed
Summary
This summary is machine-generated.

This systematic overview evaluates treatments for Menière

More Related Videos

In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears
10:27

In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears

Published on: February 21, 2018

11.2K
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

1.8K

Related Experiment Videos

Last Updated: Mar 30, 2026

Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease
04:11

Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease

Published on: April 28, 2023

2.8K
In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears
10:27

In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears

Published on: February 21, 2018

11.2K
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

1.8K

Area of Science:

  • Otolaryngology
  • Neurology
  • Evidence-Based Medicine

Background:

  • Menière's disease is a progressive, fluctuating inner ear disorder affecting adults aged 30-60.
  • Characterized by vertigo, tinnitus, hearing loss, and aural fullness.
  • Disease progression leads to persistent symptoms and hearing deterioration.

Purpose of the Study:

  • To systematically review the efficacy of various interventions for Menière's disease.
  • To assess treatments aimed at preventing attacks and delaying disease progression.
  • To evaluate combination therapy, intratympanic interventions, non-drug, and dietary approaches.

Main Methods:

  • Conducted a systematic overview of clinical evidence.
  • Searched major databases (Medline, Embase, Cochrane Library) up to July 2014.
  • Included systematic reviews and randomized controlled trials (RCTs), performing GRADE evaluations.

Main Results:

  • Screened 151 records, evaluating 51 full publications.
  • Incorporated five new systematic reviews and four new RCTs.
  • Evaluated eight PICO combinations using GRADE methodology.

Conclusions:

  • Categorized the efficacy of seven interventions for Menière's disease.
  • Included betahistine plus thiazide diuretic, caffeine restriction, intratympanic corticosteroids, intratympanic gentamicin, psychological support, salt restriction, and vestibular rehabilitation.
  • Provided a safety and effectiveness overview of these Menière's disease treatments.