[AIDS-related early mortality in Mexico between 2008 and 2012]

Related Experiment Video

Updated: Mar 30, 2026

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
19:57

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

19.5K

Omar Silverman-Retana1, Sergio Bautista-Arredondo1, Edson Serván-Mori1

  • 1Instituto Nacional de Salud Pública, Cuernavaca, Morelos, México.

Salud Publica De Mexico
|November 7, 2015
PubMed
Abstract

Insights

Most AIDS deaths in Mexico occur within six months of starting antiretroviral treatment, often due to late HIV diagnosis. Strengthening early diagnosis and care linkage is crucial for effective HIV treatment access.

Area of Science:

  • Public Health
  • Epidemiology
  • Infectious Diseases

Background:

  • Access to antiretroviral treatment (ART) is a cornerstone of HIV/AIDS management.
  • Understanding mortality patterns post-ART initiation is vital for optimizing care.
  • The System for the Administration, Logistics and Surveillance of Antiretrovirals (SALVAR) in Mexico provides a data source for such analyses.

Purpose of the Study:

  • To analyze the timing of AIDS-related mortality among patients accessing Ministry of Health facilities in Mexico.
  • To identify factors associated with early mortality after ART initiation.

Main Methods:

  • A descriptive analysis was conducted on a cohort of 41,847 patients registered in SALVAR.
  • AIDS mortality data and associated clinical/demographic profiles were examined.
  • Time-to-death analysis relative to ART initiation was performed.

Main Results:

  • A total of 3,195 patients (8.1%) died during the study period.
  • Over half (59%) of these deaths occurred within six months of ART initiation.
  • Late HIV diagnosis (CD4 count <200 cells/mL) was prevalent in 87.3% of early mortality cases.

Conclusions:

  • A significant proportion of AIDS-related deaths occur early in the course of ART.
  • Late HIV diagnosis is a major contributing factor to early mortality.
  • Enhanced HIV diagnosis and timely linkage to care are critical for improving outcomes and achieving universal ART access in Mexico.

More Related Videos

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

17.4K
Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors05:46

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

Published on: April 9, 2014

18.5K

Related Concept Videos

Retrovirus Life Cycles01:10

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
50.6K
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
1.6K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.4K
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
3.1K
Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
2.3K
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
24