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Published on: March 30, 2014
[Correcting for misclassified HIV/aids deaths in Mexico: Retrospective analysis, 1983-2012]
Lucero Cahuana-Hurtado1, Olivia Chilian-Herrera1, Sergio Bautista-Arredondo1
1Instituto Nacional de Salud Pública, Cuernavaca, Morelos, México.
Objective:
To identify and reassign misclassified AIDS deaths in Mexico, reconstructing the time series of mortality from 1983 to 2012, by state, sex, age, and affiliation to social security.
Materials And Methods:
15.5 million deaths from 1979 to 2012 were analyzed. The HIV-AIDS mortality correction was done in three phases: a) those causes directly related to AIDS; b) by miscoded deaths, and c) AIDS deaths hidden in other underlying causes of death. Age-standardized rates of mortality (SMR) were calculated by sex, affiliation to social security, and state.
Results:
107 981 AIDS deaths from 1983 to 2012 were accumulated, representing 11% of total deaths observed for the period. The SMR in men for all age groups begins to decline since 1996, while for women the decline started in 2008. A similar picture is observed for the population with / without social security. Heterogeneity is a feature for SMR by state.
Conclusion:
An easily replicable methodology for the correction of mortality from AIDS, which generates relevant information for decision making based on the evidence is presented.
Insights
This study corrected misclassified AIDS deaths in Mexico from 1983-2012. The analysis revealed declining Acquired Immunodeficiency Syndrome mortality rates, particularly after 1996 for men and 2008 for women.
Area of Science:
- Epidemiology
- Public Health
- Demography
Background:
- Accurate mortality data is crucial for understanding disease burden and guiding public health interventions.
- Misclassification of deaths, particularly for Acquired Immunodeficiency Syndrome (AIDS), can lead to underestimation of the epidemic's impact.
- Reconstructing accurate time series of AIDS mortality is essential for effective policy-making.
Purpose of the Study:
- To identify and reassign misclassified AIDS deaths in Mexico.
- To reconstruct the time series of AIDS mortality from 1983 to 2012, stratified by state, sex, age, and social security affiliation.
- To develop a replicable methodology for correcting AIDS mortality data.
Main Methods:
- Analysis of 15.5 million deaths recorded between 1979 and 2012.
- A three-phase correction process for Human Immunodeficiency Virus-Acquired Immunodeficiency Syndrome (HIV-AIDS) mortality: direct AIDS causes, miscoded deaths, and hidden AIDS deaths.
- Calculation of age-standardized mortality rates (SMR) by sex, social security status, and state.
Main Results:
- Accumulation of 107,981 AIDS deaths between 1983 and 2012, constituting 11% of total deaths.
- Significant decline in SMR for men starting in 1996 and for women in 2008.
- Similar trends observed for populations with and without social security, with notable state-level heterogeneity in SMR.
Conclusions:
- A straightforward and reproducible methodology for correcting AIDS mortality data has been established.
- The corrected data provides valuable evidence for informed decision-making in public health.
- The study highlights the importance of accurate cause-of-death ascertainment for monitoring and controlling the HIV-AIDS epidemic.
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