BEHAVIOR OF ADIPOKINES AFTER A YEAR FOLLOW-UP IN THE OBESITY OUTPATIENT CLINIC FOR CHILDREN AND ADOLESCENTS

demonstrate adipokines progression, along 12 months, in obese children and adolescents who attend the Obesity Outpatient Clinic for Children and Adolescents of the HCPA.

children and adolescents in medical treatment for obesity were followed for 12 months, assessing anthropometry, blood pressure, waist circumference, lipid profile, fasting blood sugar and insulin, inter leukine- 6, tumor necrosis factor alpha, and adiponectin in two points in time: at inclusion and after 12 months follow-up in the Obesity Outpatient Clinic for Children and Adolescents.

27 children and adolescents were assessed with median age of 10.3 years. The mean BMI z-scores lowered during this period (p < 0.01), HDL-c increased in the period (p = 0.025). The medians of adipokines did not vary during the period: IL-6 (p = 0.470), TNF-α (p = 0.753) and adiponectin (p = 0.943). There was no correlation of IL-6 and TNF-α with central and global obesity along the 12-months follow-up. Adiponectin increased in 45% of the sample, the increase being more pronounced in females.

children and adolescents in medical treatment for obesity, after one-year follow-up, did not improve their adiponectin profile.