Related Experiment Video
Updated: Mar 30, 2026

08:56
Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
Published on: April 7, 2023
1.5K
Osteoporosis: What about men?
Bryan Farford1, Jonathan Balog1, Kensler Dawson Jackson1
1Department of Family Medicine, Mayo Clinic, Jacksonville, FL, USA.
The Journal of Family Practice
|November 8, 2015
Summary
Osteoporosis affects up to 40% of men, leading to fractures and potentially fatal outcomes. This condition is often overlooked in men because it is commonly misconstrued as a women's disease.
Area of Science:
- Gerontology
- Orthopedics
- Endocrinology
Background:
- Osteoporotic fractures represent a significant health burden, accounting for up to 40% of all such injuries in men.
- Osteoporosis is frequently underestimated in men, often misdiagnosed due to its societal perception as a predominantly female condition.
Purpose of the Study:
- To highlight the prevalence and severity of osteoporosis in the male population.
- To underscore the diagnostic challenges and clinical implications of missed osteoporosis diagnoses in men.
Main Methods:
- This study synthesizes existing epidemiological data and clinical observations regarding male osteoporosis.
- A review of current diagnostic criteria and treatment guidelines for osteoporosis in men was conducted.
Main Results:
- Men sustain a substantial proportion of osteoporotic fractures, carrying significant morbidity and mortality risks.
- Delayed diagnosis in men contributes to increased fracture rates and poorer health outcomes.
Conclusions:
- There is a critical need to raise awareness of osteoporosis as a significant health issue for men.
- Improved screening, diagnosis, and management strategies are essential to address the burden of osteoporosis in the male population.
Related Concept Videos
Bone Disorders
7.6K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
7.6K
Menopause
5.1K
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
5.1K
Disorders of the Male Reproductive System
5.4K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.4K
Bone Remodeling
41.1K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
41.1K
Osteoclasts in Bone Remodeling
4.7K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
4.7K
Infertility in Males
683
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
683

