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Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET: Dopamine Movies of Cigarette Smoking
Published on: August 6, 2013
[Reconstruction of dynamic positron emission tomographic images by exploiting low rank and sparse penalty]
Xia-Ping Wei1, Xue-Wen Jiang, Xiao-Mian Ma
11School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China; Yantai Yuhuangding Hospital, Yantai 264000, China; 3Department of Radiology, Cancer Center, Guangdong General Hospital/Guangdong Academy of Medical Science, Guangzhou 510080, China.
Objective:
To propose a new method for dynamic positron emission tomographic (PET) image reconstruction using low rank and sparse penalty (L&S).
Methods:
The L&S reconstruction model was established and the split Bregman method was used to solve the optimal cost function. The one-tissue compartment model was used to simulate a set of PET 82Rb myocardial perfusion image. The L&S reconstruction method was compared with maximum likelihood expectation maximization (MLEM) method, low-rank penalty method and sparse penalty method.
Results:
The L&S reconstruction method had the smallest MSE and well maintained the feature information. The polar map created by L&S method was the most similar with the reference actual polar map.
Conclusion:
L&S reconstruction method is better than the other three methods in both visual and quantitative analysis of the PET images.
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