Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

77
Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
77
Pharmacovigilance01:19

Pharmacovigilance

1.9K
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.9K
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

347
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
347
Dosage Regimen Designs: Nomograms and Tabulations01:23

Dosage Regimen Designs: Nomograms and Tabulations

301
Nomograms and tabulations are vital tools used by clinicians to design accurate and individualized dosage regimens. These instruments provide a straightforward method for adjusting dosages based on individual patient characteristics, including age, weight, and physiological condition. The foundation of a drug's nomogram is population pharmacokinetic data collected and analyzed using specific models. This data simplifies complex equations, presenting them diagrammatically or tabularly for easy...
301
Therapeutic Drug Monitoring: Overview and Classification01:16

Therapeutic Drug Monitoring: Overview and Classification

517
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
517
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

466
Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
466

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patient displacement during recurrent rural emergency department service interruptions: a 5-year observational case study.

CJEM·2026
Same author

Persona-Driven Vignettes: A Novel Needs Assessment and Audit Tool for Faculty Development.

Cureus·2026
Same author

Sonographic assessment of fasting: emergency room sedations.

CJEM·2026
Same author

Impact on outcomes of ultra hypofractionation or hypofractionation regimens and proton or Xrays therapy in a phase III randomized controlled trial MC1635.

Frontiers in oncology·2025
Same author

Deferral of systemic therapy in patients with oligorecurrent prostate cancer treated with metastasis-directed radiotherapy.

Annals of translational medicine·2025
Same author

A Global Survey of Mental Health Treatment Experiences Among Food Allergy Patients and Caregivers.

The journal of allergy and clinical immunology. In practice·2025

Related Experiment Video

Updated: Mar 30, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.6K

Check it out: A practical tool for improving medication safety.

Terri L Warholak1, Michael T Rupp2, Amanda Zale3

  • 1College of Pharmacy, University of Arizona, Tucson, AZ..

Journal of the American Pharmacists Association : Japha
|November 9, 2015
PubMed
Summary

A prospective drug utilization review (DUR) checklist can enhance pharmaceutical care quality and patient safety in community pharmacies. Implementing this checklist improves pharmacists' DUR activities and medication therapy outcomes.

More Related Videos

Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

19.5K
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

31.6K

Related Experiment Videos

Last Updated: Mar 30, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.6K
Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

19.5K
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

31.6K

Area of Science:

  • Pharmacy Practice
  • Medication Safety
  • Health Services Research

Background:

  • Prospective drug utilization review (DUR) is crucial for ensuring medication safety.
  • Current community pharmacy workflows may not consistently incorporate all essential DUR elements.
  • Regulatory requirements, such as the Omnibus Budget Reconciliation Act of 1990 (OBRA '90), mandate specific DUR components.

Purpose of the Study:

  • To propose the integration of a prospective DUR checklist into routine prescription order processing.
  • To enhance the quality and safety of pharmaceutical care in community practice settings.
  • To ensure compliance with OBRA '90 and state pharmacy practice acts.

Main Methods:

  • Development of a comprehensive prospective DUR checklist.
  • The checklist was designed to encompass all OBRA '90 mandated DUR elements.
  • The checklist aligns with requirements from most state pharmacy practice acts.

Main Results:

  • A simple DUR checklist, when integrated into workflow, can significantly improve prospective DUR activities.
  • Implementation can lead to enhanced safety of medication therapy for patients.
  • The study proposes a practical tool for community pharmacy settings.

Conclusions:

  • Routine incorporation of a prospective DUR checklist can elevate the quality of pharmaceutical care.
  • This checklist supports improved medication safety and patient outcomes.
  • Development of quality metrics is recommended to ensure consistent pharmacist performance of DUR responsibilities.