Gastroesophageal reflux disease. Recognizing and managing major complications

Complications of gastroesophageal reflux disease are reassuringly few, considering the widespread morbidity from reflux disease. The major ones are bleeding, ulcer, stricture, and carcinoma. These serious, disabling complications, although infrequent, can be life-threatening. Management is not entirely satisfactory. Improved medical and surgical therapy awaits further clinical research.