[Indications for the use of prednisolone in tuberculosis]

To study the nature of lesions in the lungs developing as a result of using glucocorticoids in combined therapy of tuberculosis, two groups of new cases of infiltrative tuberculosis were observed. 51 patients were treated with the use of prednisolone and 23 patients were treated with antibacterial drugs alone. In addition, studies were performed on two groups of noninbred albino rats infected with mycobacteria Bovinus-8. It was shown that by changing the nature of the tissue reactions prednisolone promoted formation of tuberculoma type foci in the lung tissue and prolonged the periods of cavern closing.