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Infective endocarditis: a tertiary referral centre experience from Turkey
Fahriye Vatansever Agca1, Necmiye Demircan2, Tezcan Peker1
1Department of Cardiology, Yuksek Ihtisas Training and Research Hospital Bursa, Turkey.
Infective endocarditis (IE) in Turkey affects younger patients, with prosthetic valve disease increasingly common. Early surgical intervention is crucial for reducing high mortality rates in these infective endocarditis cases.
Area of Science:
- Cardiology
- Infectious Diseases
- Clinical Medicine
Background:
- Infective endocarditis (IE) remains a significant clinical challenge.
- Understanding current IE demographics and risk factors is essential for effective management.
Purpose of the Study:
- To characterize the epidemiological and clinical features of infective endocarditis (IE) in a specific region of Turkey.
- To identify trends in predisposing factors and causative agents of IE.
Main Methods:
- Retrospective analysis of 85 patients diagnosed with IE between 2009 and 2014.
- Diagnosis confirmed using modified Duke criteria.
- Data collected from hospital archives.
Main Results:
- The mean age of IE patients was 52 years, with a male predominance.
- Prosthetic valve disease was the most common predisposing factor (40%), followed by native valve involvement (47%).
- Staphylococci were the most frequent pathogens (27%), and the in-hospital mortality rate was 36%.
Conclusions:
- Infective endocarditis in Turkey presents in relatively young individuals.
- Prosthetic and degenerative valve diseases are replacing rheumatic heart disease as primary predisposing factors in developed areas.
- Surgical intervention is vital for improving outcomes and reducing mortality in IE patients.
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