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Association of tea consumption and the risk of thyroid cancer: a meta-analysis
Sugang Ma1, Chunyan Wang2, Jiandong Bai1
1Department of General Surgery, Zhangqiu People's Hospital Ji'nan, Shandong, 250200, P.R. China.
Objectives:
Epidemiological studies evaluating the association of tea consumption and the risk of thyroid cancer risk have produced inconsistent results. Thus, we conducted a meta-analysis to assess the relationship between tea consumption and thyroid cancer risk.
Methods:
Pertinent studies were identified by a search in PubMed and Web of Knowledge. The random effect model was used based to combine the results. Publication bias was estimated using Egger's regression asymmetry test.
Results:
Finally, 11 articles with 14 studies (2 cohort studies and 12 case-control studies) involving 2,955 thyroid cancer cases and 106,447 participants were included in this meta-analysis. The relative risk (95% confidence interval) of thyroid cancer for the highest versus the lowest category of tea consumption was 0.774 (95% CI = 0.619-0.967), and the associations were also significant in Europe and America, but not in the Asia. No publication bias was found.
Conclusions:
Our analysis indicated that higher tea consumption may have a protective effect on thyroid cancer, especially in Europe and America.
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