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In vitro screens from CNS, liver and kidney for systemic toxicity

C A Tyson¹, N H Stacey

¹SRI International, Menlo Park, California.

Toxicology and Industrial Health

|January 1, 1989

Abstract:

The development and evaluation of in vitro systems from target organs for preliminary assessments of the potential for systemic toxic effects has been receiving increased attention. This review presents a synopsis of progress made in developing toxicity screens for three common target organs and identifies further work needed for more complete validation.

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