Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Crystal Growth: Principles of Crystallization01:25

Crystal Growth: Principles of Crystallization

5.9K
Crystallization is a phase transformation process in which crystals are precipitated from a supersaturated solution or formed from other sources. During crystallization, atoms or molecules arrange themselves into a well-defined, rigid crystal lattice to minimize energy.
Initiating crystallization involves manipulating the concentration of the solute and the temperature of the solution. Since crystal growth occurs when the ratio of concentration and solubility of the solute in the solvent...
5.9K
Recrystallization: Solid–Solution Equilibria01:10

Recrystallization: Solid–Solution Equilibria

4.7K
Recrystallization is a purification technique used to separate impurities from solid compounds. In this technique, no chemical reactions occur. Instead, it exploits physical properties only, specifically, the solubility differences between the desired compound and impurities, either at a single temperature or at different temperatures, and under other selected conditions. The solid-solution equilibrium (solubility equilibrium) of each component in the solution represents a binary phase...
4.7K
Polymer Classification: Crystallinity01:21

Polymer Classification: Crystallinity

4.2K
Unlike ionic or small covalent molecules, polymers do not form crystalline solids due to the diffusion limitations of their long-chain structures. However, polymers contain microscopic crystalline domains separated by amorphous domains.
Crystalline domains are the regions where polymer chains are aligned in an orderly manner and held together in proximity by intermolecular forces. For example, chains in the crystalline domains of polyethylene and nylon are bound together by van der Waals...
4.2K
Precipitation Processes01:12

Precipitation Processes

6.5K
The experimental conditions in a gravimetric analysis should be optimized to maximize the particle size and purity of the obtained precipitate. Ideally, the concentration of the precipitating reagent should be low with effective stirring to maintain low relative supersaturation for the growth of large crystals. In homogeneous precipitation, the precipitant is slowly generated by a chemical reaction in the solution to avoid local reagent excesses. For example, urea decomposes gradually to...
6.5K
Precipitate Formation and Particle Size Control01:16

Precipitate Formation and Particle Size Control

7.1K
In precipitation gravimetry, the precipitating agent should react specifically or selectively with the analyte. While a specific reagent reacts with the analyte alone, a selective reagent can react with a limited number of chemical species.
The obtained precipitate should be either a pure substance of known composition or easily converted to one by a simple process, such as ignition or drying. In addition, the precipitate should be insoluble and easily filterable. In general, filterability...
7.1K
Colloidal precipitates01:09

Colloidal precipitates

6.8K
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
6.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Green Processing Strategy for the Formation of Electrochromic Metal-Organic Assemblies.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Electrolyte-Guided Selectivity Unlocks Pathway Control in Electrochemical Olefin Functionalization.

Journal of the American Chemical Society·2026
Same author

Formation of S- and Z-twist supramolecular micro-ropes by peptide stereoisomers.

Nature communications·2026
Same author

CO<sub>2</sub> Conversion by a Metal-Coordinated Single Amino Acid Carbonic Anhydrase Enzyme Mimic.

ACS applied materials & interfaces·2026
Same author

Elucidating Structural Disorder in a Polymeric Layered Material: The Case of Sodium Poly(heptazine imide) Photocatalyst.

Nano letters·2025
Same author

Direct chiroptical correlation of dissymmetric crystal morphologies.

Nature communications·2025

Related Experiment Video

Updated: Mar 30, 2026

Growing Protein Crystals with Distinct Dimensions Using Automated Crystallization Coupled with In Situ Dynamic Light Scattering
09:15

Growing Protein Crystals with Distinct Dimensions Using Automated Crystallization Coupled with In Situ Dynamic Light Scattering

Published on: August 14, 2018

11.1K

Precrystalline Aggregates Enable Control over Organic Crystallization in Solution.

Chen Shahar1, Sounak Dutta1, Haim Weissman1

  • 1Department of Organic Chemistry, Weizmann Institute of Science, Rehovot 76100 (Israel) http://www.weizmann.ac.il/oc/boris/

Angewandte Chemie (International Ed. in English)
|November 11, 2015
PubMed
Summary
This summary is machine-generated.

Controlling organic crystallization is challenging. This study reveals that amorphous aggregates precede crystal formation, enabling control over crystallization by manipulating these precrystalline states.

Keywords:
crystallizationhydrophobic interactionsperylene diimidepolymorphismprenucleation

More Related Videos

Optimization of Crystal Growth for Neutron Macromolecular Crystallography
12:29

Optimization of Crystal Growth for Neutron Macromolecular Crystallography

Published on: March 13, 2021

6.0K
Optimizing the Growth of Endothiapepsin Crystals for Serial Crystallography Experiments
09:52

Optimizing the Growth of Endothiapepsin Crystals for Serial Crystallography Experiments

Published on: February 4, 2021

2.8K

Related Experiment Videos

Last Updated: Mar 30, 2026

Growing Protein Crystals with Distinct Dimensions Using Automated Crystallization Coupled with In Situ Dynamic Light Scattering
09:15

Growing Protein Crystals with Distinct Dimensions Using Automated Crystallization Coupled with In Situ Dynamic Light Scattering

Published on: August 14, 2018

11.1K
Optimization of Crystal Growth for Neutron Macromolecular Crystallography
12:29

Optimization of Crystal Growth for Neutron Macromolecular Crystallography

Published on: March 13, 2021

6.0K
Optimizing the Growth of Endothiapepsin Crystals for Serial Crystallography Experiments
09:52

Optimizing the Growth of Endothiapepsin Crystals for Serial Crystallography Experiments

Published on: February 4, 2021

2.8K

Area of Science:

  • Materials Science
  • Chemical Engineering
  • Physical Chemistry

Background:

  • Organic crystallization in solution is difficult to control.
  • Aromatic amphiphiles, like perylene diimide derivatives, are key materials with tunable properties.

Purpose of the Study:

  • To investigate the crystallization process of aromatic amphiphiles in aqueous media.
  • To demonstrate a new strategy for controlling organic crystallization through precrystalline state manipulation.

Main Methods:

  • Observation of crystallization using perylene diimide-based aromatic amphiphiles in aqueous solutions.
  • Analysis of the evolution from amorphous spherical aggregates to crystalline phases.
  • Tuning hydrophobicity to regulate molecular structure and crystal formation.

Main Results:

  • Crystallization initiates within initially formed amorphous spherical aggregates.
  • The solvation of prenucleation phases drives the formation of crystals with distinct structures and photofunctions.
  • Hydrophobicity tuning allows regulation of crystal evolution, yielding different products or preventing crystallization.

Conclusions:

  • Precrystalline states, specifically amorphous aggregates, play a crucial role in organic crystal evolution.
  • Manipulation of these precrystalline states offers a novel strategy for precise control over organic crystallization processes.
  • This approach allows for the design of tailored crystalline materials with specific structures and functionalities.