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Updated: Mar 30, 2026

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
Published on: October 18, 2019
Iron-catalyzed transfer hydrogenation of imines assisted by an iron-based Lewis acid
Hui-Jie Pan1, Teng Wei Ng1, Yu Zhao1
1Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Republic of Singapore. zhaoyu@nus.edu.sg.
Abstract:
An iron-catalyzed transfer hydrogenation of N-aryl and N-alkyl imines using isopropanol as the hydrogen donor is reported for the first time. A combination of two iron complexes serving different roles is the key for the success of this catalytic system. As a result, an environmentally friendly and precious metal-free transfer hydrogenation of imines has been developed. The use of a suitable co-catalyst as an activator not only led to efficient transfer hydrogenation, but also showed potential in enantioselective transformation.
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