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Medulloblastoma With Obstructive Hydrocephalus in a Young Infant
Ruth Abaya1, Jean B Belasco, Angela M Ellison
1From the Divisions of *Emergency Medicine and †Oncology, Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Insights
Medulloblastoma, a common infant posterior fossa tumor, can present unusually. This case highlights a 2-month-old infant with poor feeding and lethargy due to medulloblastoma.
Area of Science:
- Pediatric Oncology
- Neuro-oncology
Background:
- Medulloblastoma is the most frequent posterior fossa tumor in infants.
- Posterior fossa tumors in neonates exhibit diverse clinical presentations.
Observation:
- A 2-month-old infant presented with nonspecific symptoms including poor feeding and lethargy.
- A notable neurological sign was a fixed downward gaze.
Findings:
- Computed tomography identified a posterior fossa mass.
- Pathological examination confirmed the mass as medulloblastoma.
Implications:
- This case underscores the variability in medulloblastoma presentation in young infants.
- Highlights the importance of considering medulloblastoma in neonates with atypical neurological signs.
Abstract:
Medulloblastoma is the most common posterior fossa tumor diagnosed in young infants. The presentation of posterior fossa tumors in neonates is highly variable. We report the case of a 2-month-old child who presented with poor feeding and lethargy and was noted to have a fixed downward gaze. Head computed tomography revealed a posterior fossa mass that was pathologically consistent with a medulloblastoma. This case demonstrates the uncommon presentation of posterior fossa tumors in young infants.
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