Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 30, 2026

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
07:03

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

1.6K

Active droplet generation in microfluidics.

Zhuang Zhi Chong1, Say Hwa Tan2, Alfonso M Gañán-Calvo3

  • 1School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore.

Lab on a Chip
|November 12, 2015
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correspondence on "Mass Balance Tracing of <i>In Vivo</i> Biodistribution, Relocation, and Excretion of Europium-Doped Micro/Nanoplastics in Rats".

Environmental science & technology·2026
Same author

Steady-State and Dynamic Behavior of Geometry-Tunable Microfluidic Passive Flow Regulators.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Exploiting Device Deformability for Fluid and Particle Manipulation.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Transdermal needle-free drug delivery approaches and activation mechanism.

Materials today. Bio·2026
Same author

Integrated microfluidic platform for inertial separation and encapsulation of single cells in droplets.

Lab on a chip·2026
Same author

Intrinsic and Water-Triggered Hydrophilicity in Tween 20-PDMS Composites for Dynamic and Long-Term Wettability Control.

Small (Weinheim an der Bergstrasse, Germany)·2026

This review explores active droplet generation methods for microfluidics. It categorizes techniques by energy source, crucial for advanced lab-on-a-chip applications requiring precise droplet control.

Area of Science:

  • Microfluidics
  • Chemical Engineering
  • Biotechnology

Background:

  • Micron-sized droplet generation is vital for droplet-based microfluidics.
  • Droplets serve as self-contained reaction platforms in lab-on-a-chip systems.
  • Increasingly complex applications necessitate sophisticated control over droplet generation.

Purpose of the Study:

  • To present the state-of-the-art in active droplet generation concepts.
  • To categorize active droplet generation methods based on induced energy.
  • To highlight the importance of energy imbalance at liquid/liquid interfaces for droplet breakup.

Main Methods:

  • Review of existing literature on active droplet generation techniques.
  • Categorization of methods based on the type of energy input (e.g., electrical, thermal, mechanical).

More Related Videos

Glass-Based Devices to Generate Drops and Emulsions
08:45

Glass-Based Devices to Generate Drops and Emulsions

Published on: April 5, 2022

3.4K
High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices
10:22

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

14.3K

Related Experiment Videos

Last Updated: Mar 30, 2026

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology
07:03

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

1.6K
Glass-Based Devices to Generate Drops and Emulsions
08:45

Glass-Based Devices to Generate Drops and Emulsions

Published on: April 5, 2022

3.4K
High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices
10:22

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

14.3K
  • Analysis of droplet breakup mechanisms driven by interfacial energy imbalance.

    • Main Results:

    • Comprehensive overview of various active droplet generation strategies.
    • Classification of techniques according to their underlying physical principles.
    • Identification of key factors influencing droplet stability and breakup.

    Conclusions:

    • Active droplet generation offers precise control for microfluidic applications.
    • Understanding energy dynamics at interfaces is key to optimizing droplet formation.
    • This review provides a framework for selecting and developing advanced droplet generation systems.