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Published on: June 30, 2014
Psychiatric disorders in patients with multiple sclerosis
Ana Claudia de Cerqueira1, Patricia Semionato de Andrade2, Jose Maurício Godoy Barreiros2
1Federal University of Rio de Janeiro, Institute of Psychiatry.
High rates of depression and suicide risk were found in Brazilian multiple sclerosis patients. These mood disorders require systematic investigation, independent of disability or disease duration.
Area of Science:
- Neuroscience
- Psychiatry
- Epidemiology
Background:
- Multiple sclerosis (MS) is a chronic neurological condition.
- Psychiatric disorders, especially mood and anxiety disorders, are common comorbidities in MS.
- Understanding the prevalence and correlates of these disorders is crucial for patient care.
Purpose of the Study:
- To determine the frequency of psychiatric disorders in Brazilian outpatients with MS.
- To specifically assess mood and anxiety disorders.
- To correlate psychiatric findings with sociodemographic and clinical data.
Main Methods:
- A cross-sectional study design was employed.
- Patients were consecutively evaluated using a structured interview (MINI) for psychiatric disorders.
- The Beck Depression Inventory and Beck Anxiety Inventory assessed symptom severity.
Main Results:
- The prevalence of major lifelong depression was 36.6% in the study population.
- A high risk of suicide was associated with depression.
- No significant correlation was found between depression, disability level, or disease duration.
Conclusions:
- Mood disorders are highly prevalent in patients with multiple sclerosis.
- Depression is a significant factor associated with suicide risk in this population.
- Systematic screening for depression is recommended for MS patients.
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