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Flow Cytometric Analysis of Particle-bound Bet v 1 Allergen in PM10
Published on: November 19, 2016
Association of urban particle numbers and sources with lung function among children with asthma or allergies
Ya-Ru Li1, Li-Ting Feng2, Bing-Yu Chen3
1Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, 17 Xu-Zhou Road, Taipei 10055, Taiwan.
Abstract:
Previous studies have reported sources of particle number pollution in urban air, but have not evaluated relationships between respiratory health and these sources. We compared, among children with asthma or allergies, the associations of spirometric lung functions with increased exposure to source-specific versus size-segregated particle number concentrations (PNC). Hourly measurements of PNC were acquired from the aerosol Supersite in New Taipei, Taiwan. Spirometry (FVC, FEV1, and FEF) was recorded monthly for 59 children with asthma or allergies at five schools during 2007-2008. After co-pollutant adjustment for ozone, we found a 0.21 and 0.17 L decrease in FVC [95% confidence interval (CI): -0.35, -0.06 L] and FEV1 (95% CI: -0.32, -0.03 L), respectively, with an interquartile range increase (1879.7#/cm(3)) in secondary aerosol contribution observed on the previous day. In addition, we found no significant associations of FVC with accumulation mode (0.1 μm
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