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Published on: September 19, 2019
Dry beriberi preceded Wernicke's encephalopathy: Thiamine deficiency after laparoscopic sleeve gastrectomy
1Division of Child Neurology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Insights
Pediatric bariatric surgery patients can develop Wernicke
Area of Science:
- Neurology
- Nutritional Science
- Bariatric Surgery
Background:
- Pediatric obesity is a growing concern, with bariatric surgery considered for severe cases.
- Patients undergoing bariatric surgery, particularly abroad, may face inadequate postoperative care.
- Restrictive bariatric procedures like laparoscopic sleeve gastrectomy are increasingly common.
Observation:
- A 17-year-old patient developed dry beriberi and Wernicke's encephalopathy after sleeve gastrectomy.
- Symptoms arose due to nausea leading to cessation of multivitamin supplementation.
- Diagnosis was confirmed via serum thiamine levels and brain MRI.
Findings:
- Thiamine deficiency (leading to Wernicke's encephalopathy) can occur even after restrictive bariatric surgery.
- Risk factors include dietary noncompliance, poor follow-up, and severe nausea/vomiting.
- Prompt thiamine supplementation reversed ophthalmological symptoms, but neuropathy required rehabilitation.
Implications:
- Healthcare providers must be vigilant for Wernicke's encephalopathy in post-bariatric surgery patients.
- Early identification of vague sensory symptoms is crucial for timely thiamine deficiency diagnosis.
- Increased bariatric surgeries necessitate greater awareness of potential nutrient deficiencies.
Abstract:
In recent times, pediatric obesity has become widely prevalent. If first-line treatment with lifestyle modification fails, bariatric surgery may be indicated for severely obese patients. Many patients now travel abroad to get these surgeries done. Some of these patients receive inadequate postoperative care. We described a morbidly obese 17-year-old girl who had a laparoscopic sleeve gastrectomy procedure for weight loss. Due to severe nausea, she stopped her multivitamin supplementation. Within a few weeks, she developed symptoms of dry beriberi was soon followed by classic symptoms of Wernicke's encephalopathy. The prompt diagnosis was made with confirmation from serum thiamine level and brain magnetic resonance imaging. Thiamine supplementation reversed ophthalmological symptoms promptly. However, the patient needed inpatient rehabilitation for neuropathy. This case describes that thiamine deficiency can occur after restrictive bariatric surgery, despite lower risk of malnutrition in the absence of intestinal bypass procedure. This report highlights that in the presence of risk factors: dietary noncompliance, inadequate follow-up, and severe nausea with and without vomiting can precipitate the development of Wernicke's encephalopathy, even after restrictive surgery. Physicians may increasingly encounter thiamine and other nutrient deficiencies in increasing numbers due to increasing prevalence of obesity disorders and availability of bariatric surgeries. This report also emphasized the importance of identifying vague sensory symptoms in thiamine deficiency.
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