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Related Concept Videos

Tumor Progression02:07

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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Targeted Cancer Therapies02:57

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Translational progress on tumor biomarkers.

Hongwei Guo1, Xiaolin Zhou1, Yi Lu1

  • 1Key Laboratory of Longevity and Aging-Related Diseases, Ministry of Education Nanning, China ; Center for Translational Medicine, Guangxi Medical University Nanning, China.

Thoracic Cancer
|November 12, 2015
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Summary
This summary is machine-generated.

Translational medicine accelerates cancer research by linking basic science to clinical practice. This review highlights recent advances in tumor biomarkers, aiming to improve cancer patient survival and quality of life.

Keywords:
Targeted therapytranslational medicinetumor biomarkers

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Area of Science:

  • Oncology
  • Translational Medicine
  • Biomarker Discovery

Background:

  • Basic cancer research requires clinical application for patient benefit.
  • Translational medicine bridges the gap between laboratory findings and clinical practice.
  • Novel tumor biomarkers are crucial for improving cancer patient outcomes.

Purpose of the Study:

  • To review recent achievements in tumor biomarker research.
  • To discuss the clinical application prospects of these biomarkers.
  • To emphasize the role of translational medicine in oncology.

Main Methods:

  • Literature review of translational medicine in cancer biology.
  • Analysis of recent advancements in tumor biomarker identification and characterization.
  • Evaluation of clinical application potential.

Main Results:

  • Significant progress has been made in identifying and characterizing novel tumor biomarkers.
  • Translational medicine approaches are increasingly being applied to cancer biomarker research.
  • Several biomarkers show promise for clinical application.

Conclusions:

  • Translational medicine is vital for translating basic cancer research into clinical advancements.
  • Continued focus on tumor biomarkers is essential for improving cancer patient survival and quality of life.
  • Future research should prioritize clinical relevance and application of biomarker findings.