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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
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Stem Cell Culture01:17

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Adult Stem Cells01:33

Adult Stem Cells

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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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Embryonic Stem Cells00:58

Embryonic Stem Cells

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Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
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Embryonic Stem Cells00:57

Embryonic Stem Cells

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
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iPS Cell Differentiation01:22

iPS Cell Differentiation

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The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
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Related Experiment Video

Updated: Mar 30, 2026

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
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Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

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Stem-cell therapy for erectile dysfunction.

Maarten Albersen1, Ching-Shwun Lin2, Tom Lue2

  • 1Laboratory for Experimental Urology, Gene and Stem Cells Applications, Department of Development and Regeneration, University of Leuven, Leuven, Belgium.

Arab Journal of Urology
|November 12, 2015
PubMed
Summary
This summary is machine-generated.

Stem cell (SC) therapies show promise for treating erectile dysfunction (ED) by addressing underlying causes, not just symptoms. Clinical trials are underway to confirm these regenerative medicine findings in men with ED.

Keywords:
(A)(E)(H)(M) SC, (adult) (embryonic) (haematopoietic) (mesenchymal) stem cell(e)(n)NOS, (endothelial) (neuronal) NO synthaseAD, adipose tissue-derivedAgeingBM, bone marrow-derivedCC, corpus cavernosumCNI, cavernous nerve injuryCavernous nerve injuryDiabetesED, erectile dysfunctionGFP, green fluorescent proteinMD, muscle-derivedMPG, major pelvic ganglionNO, nitric oxidePD, Peyronie’s diseasePDE5 (I), phosphodiesterase type 5 (inhibitor)Peyronie’s diseaseRP, radical prostatectomySVF, stromal vascular fraction

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Area of Science:

  • Regenerative Medicine
  • Urology
  • Stem Cell Biology

Background:

  • Erectile dysfunction (ED) is a prevalent sexual disorder, with current treatments offering temporary symptom relief.
  • Stem cell (SC) therapies are emerging as a potential solution to restore erectile function by targeting the root causes of ED.

Purpose of the Study:

  • To review contemporary research on the application of stem cells (SCs) for treating erectile dysfunction (ED).
  • To provide an overview of preclinical and clinical studies investigating SC-based therapies for ED.

Main Methods:

  • Extensive literature search of English-language publications (1966-2013) using major scientific databases.
  • Keywords included 'erectile dysfunction', 'stem cells', and various SC types, conditions, and animal models.

Main Results:

  • Fifty-four relevant papers were identified, encompassing original research and reviews.
  • Preclinical studies consistently demonstrated beneficial effects of SC therapy on erectile function recovery across various conditions.
  • Evidence regarding the precise mechanisms of action of SC therapy varied across studies.

Conclusions:

  • Preclinical research strongly supports SC-based medicine as a potential cure for ED, moving beyond symptom management.
  • Growing interest in regenerative medicine for sexual health is evident.
  • Clinical trials are actively recruiting patients to validate these promising preclinical findings in humans.