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Antigens Involved in Adaptive Immunity01:26

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Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
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Hypoallergenic molecules for subcutaneous immunotherapy.

Laurian Jongejan1, Ronald van Ree1,2, Lars K Poulsen2

  • 1a Department of Experimental Immunology , Academic Medical Center , Amsterdam , The Netherlands.

Expert Review of Clinical Immunology
|November 13, 2015
PubMed
Summary

Allergen-specific immunotherapy (AIT) shows promise for food allergies, though its effectiveness is still being studied. Recent advances in a proof-of-concept study may spur further research and development in precision allergy medicine.

Keywords:
FASTallergyfishhypoallergenimmunotherapyparvalbuminpeach

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Area of Science:

  • Immunology
  • Allergy Research
  • Precision Medicine

Background:

  • Allergies affect a significant portion of the population, with limited curative options currently available.
  • Allergen-specific immunotherapy (AIT) has demonstrated success in managing insect and venom allergies.
  • The efficacy of AIT for food allergies remains an area requiring further investigation.

Discussion:

  • This editorial highlights recent progress in a proof-of-concept study for food allergy immunotherapy, FAST (Food Allergy Specific Immunotherapy).
  • The study's findings could stimulate greater interest from the biomolecular and pharmaceutical industries.
  • This may encourage investment in similar immunology-driven precision medicine initiatives within the allergy field.

Key Insights:

  • Recent advances in food allergy immunotherapy research are detailed.
  • The FAST study provides a proof of concept for targeted allergy treatments.
  • Potential for increased industry engagement in precision allergy medicine.

Outlook:

  • Further research into AIT for food allergies is anticipated.
  • The development of immunology-driven precision medicine for allergies is a growing area.
  • Collaboration between research and industry is crucial for advancing allergy treatments.