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Effect of co-morbidities on the development of oral feeding ability in pre-term infants: a retrospective study
Maria Lorella Giannì1, Patrizio Sannino2, Elena Bezze2
1Fondazione I.R.C.C.S. Ca Granda Ospedale Maggiore Policlinico, Neonatal Intensive Care Unit Department of Clinical Science and Community Health, University of Milan, Via Commenda 12, 20122 Milano, Italy.
Insights
Pre-term infants often struggle with independent oral feeding. Comorbidities like bronchopulmonary dysplasia and gastrointestinal surgery significantly delay feeding independence in premature infants.
Area of Science:
- Neonatology
- Pediatric Gastroenterology
- Developmental Pediatrics
Background:
- Preterm infants often face challenges achieving independent oral feeding.
- This difficulty can impede nutritional status and prolong hospitalization.
Purpose of the Study:
- To investigate the impact of comorbidities on the timing of full oral feeding achievement in preterm infants.
- To identify specific factors influencing feeding independence in this vulnerable population.
Main Methods:
- Retrospective, single-center observational study.
- Analysis of neonatal and feeding data from 84 preterm infants (gestational age <32 weeks).
- Multiple linear regression used to evaluate the effect of comorbidities on feeding independence.
Main Results:
- The mean postmenstrual age for achieving full oral feeding was 36.7 weeks.
- Low birth weight was independently associated with delayed feeding.
- Bronchopulmonary dysplasia and gastrointestinal surgery also independently predicted later feeding achievement.
Conclusions:
- Comorbidities significantly influence the timeline for achieving oral feeding in preterm infants.
- Early identification and management of these factors are crucial for optimizing infant nutrition and discharge planning.
Abstract:
Pre-term infants frequently experience difficulties in attaining independent oral feeding, thus delaying the achievement of an adequate nutritional status and hospital discharge. The aim of this retrospective, single-centre, observational study was to investigate the effect of co-morbidities on the timing of the achievement of full oral feeding in pre-term infants. The neonatal and feeding data of 84 infants born at a gestational age of <32 weeks were collected, and the effect of co-morbidities on the achievement of feeding independence was evaluated using multiple linear regression analysis. The mean postmenstrual age at the time of the achievement of full oral feeding was 36.7 ± 3.68 weeks (range 33-53) weeks. The multiple linear regression analysis showed that a low birth weight, the occurrence of bronchopulmonary dysplasia, and the need for gastrointestinal surgical procedures were independently associated with a higher postmenstrual age at achievement of full oral feedings.
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