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Vaccine candidates for malaria: what's new?
Eizo Takashima1, Masayuki Morita1, Takafumi Tsuboi1
1a Division of Malaria Research, Proteo-Science Center , Ehime University , Matsuyama , Ehime 790-8577 , Japan.
Expert Review of Vaccines
|November 13, 2015
Abstract:
Although it is more than a decade since the parasite genome information was obtained, standardized novel genome-wide selection/prioritization strategies for candidacy of malaria vaccine antigens are still sought. In the quest to systematically identify candidates, it is impossible to overemphasize the usefulness of wheat germ cell-free technology in expressing quality proteins for the post-genome vaccine candidate discovery.
Keywords:
Plasmodium falciparumRTSS/AS01antibody profiling approachmalariapost-genomereverse vaccinologysubunit vaccinevaccine candidate discoverywhole-parasite vaccine
