Atypical chorioretinal coloboma in a Golden Retriever: a retinographic, fluoroangiographic, and optical coherence tomography study
Related Experiment Video
Updated: Mar 30, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Elisa M Gonzalez-Alonso-Alegre1, Alfonso Rodriguez-Alvaro2, Javier Esteban-Martín3
1Departamento de Medicina y Cirugía Animal, Facultad de Veterinaria de la Universidad Complutense de Madrid, Hospital Clínico Veterinario Complutense, Avda. Puerta de Hierro s/n, 28040, Madrid, Spain. elisag@ucm.es.
Purpose:
To report a case of canine atypical chorioretinal coloboma where ophthalmoscopic, fluoroangiographic and optical coherence tomography characteristics are described.
Animal Studied:
A 2-year-old Golden Retriever dog in which routine ophthalmoscopic examination allowed diagnosis of a posterior coloboma on the left eye.
Procedures:
Retinography, fluorescein angiography, and optical coherence tomography were performed to characterize the lesion of the left fundus.
Results:
Ophthalmoscopy revealed a pigmented circumscribed lesion dorsal to the optic nerve of the left fundus, surrounded by small areas of hyper-reflectivity and retinal vessels with an abnormal pattern. Fluoroangiography revealed a constant hypofluorescence of the defect and a complete altered vascular pattern associated with the coloboma. Optical coherence study demonstrated an important craterlike depression showing an atrophic neurosensory retina, and a lack of retinal pigment epithelium and choroidal tissue.
Conclusions:
Fluoroangiographic and optical coherence tomographic studies of an atypical chorioretinal coloboma in a dog are reported for the first time. Both imaging techniques are of great importance to characterize this type of congenital defects.

