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Amantadine-induced livedo reticularis--Case report
Maria Victória Quaresma1, Ana Carolina Dias Gomes2, Aline Serruya1
1Santa Casa da Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Anais Brasileiros De Dermatologia
|November 13, 2015
Summary
Livedo reticularis, a vascular condition causing skin discoloration, can be drug-induced. Discontinuing amantadine improved a Parkinson's patient's chronic livedo reticularis.
Area of Science:
- Vascular Medicine
- Dermatology
Background:
- Livedo reticularis is a vascular condition characterized by a reticular pattern of cyanosis, pallor, and erythema.
- It can be congenital or acquired, with idiopathic vasospasm being the most common acquired cause.
Observation:
- Drug-induced livedo reticularis is less common but associated with certain medications like amantadine and norepinephrine.
- This case report details a patient with Parkinson's disease experiencing chronic livedo reticularis.
Findings:
- The patient's chronic livedo reticularis was linked to amantadine use.
- Discontinuation of amantadine led to significant improvement in the patient's condition.
Implications:
- This case highlights the importance of considering drug-induced causes for livedo reticularis, particularly amantadine.
- Reversible cyanosis suggests prompt identification and removal of the causative agent are crucial for managing vascular conditions.