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Acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigs
Apóstolo Ferreira Martins1, Naida Cristina Borges2, Priscila Vaz Coutinho2
1School of Veterinary Medicine and Zootechny, Universidade Federal de Goiás, Goiania, GO, Brazil.
Purpose:
To assess the systemic response of pigs to the intraperitoneal implantation of polypropylene mesh associated with chitosan-based film with a degree of deacetylation of 95%.
Methods:
Blood samples were collected 24 hours before, and two and seven days after surgery. Systemic reactions were evaluated based on white blood cell count, C-reactive protein, and total serum protein, albumin and globulin levels.
Results:
The systemic response was proportional to the composite response induced by polypropylene mesh, and the tissue inflammatory response was higher in the PP group (p=0.0033).
Conclusion:
The polypropylene mesh/chitosan-based film composite did not elicit a systemic response in pigs.
