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Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques
Published on: March 13, 2015
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HemaSpot, a Novel Blood Storage Device for HIV-1 Drug Resistance Testing
K Brooks1, A DeLong2, M Balamane1
1Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
Journal of Clinical Microbiology
|November 13, 2015
Abstract:
HemaSpot, a novel dried-blood storage filter device, was used for HIV-1 pol resistance testing in 30 fresh United States blood samples and 54 previously frozen Kenyan blood samples. Genotyping succeeded in 79% and 58% of samples, respectively, improved with shorter storage and higher viral load, and had good (86%) resistance mutation concordance to plasma.
