[Primary liver tumours in childhood]

Area of Science:

• Pediatric Radiology
• Hepatology
• Medical Imaging

Background:

• Focal liver lesions exhibit varying prevalence in pediatric versus adult populations.
• Accurate diagnosis of pediatric liver tumors is crucial for appropriate management.
• Contrast-enhanced ultrasound (CEUS) is a valuable tool in evaluating liver lesions.

Purpose of the Study:

• To discuss pediatric liver tumors based on histopathology and contrast-enhanced ultrasound (CEUS) features.
• To support the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) Pediatric Registry.
• To gather data on the safety and applications of ultrasound contrast agents in pediatric patients.

Main Methods:

• Review of histopathological criteria for pediatric liver tumors.
• Analysis of contrast-enhanced ultrasound (CEUS) features of pediatric liver lesions.
• Data collection through the EFSUMB Pediatric Registry.

Main Results:

• Specific histopathological findings associated with common pediatric liver tumors.
• Characteristic CEUS patterns differentiating various pediatric liver lesions.
• Initial data on the safety and efficacy of ultrasound contrast agents in children.

Conclusions:

• Histopathology and CEUS are essential for diagnosing pediatric liver tumors.
• The EFSUMB Pediatric Registry is vital for advancing knowledge on ultrasound contrast agents in children.
• Further data collection will refine the understanding of CEUS in pediatric liver lesion evaluation.