Prevalence Estimates of Complicated Syphilis
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Updated: Mar 30, 2026

Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering
Published on: January 24, 2025
Julia C Dombrowski1, Rolf Pedersen, Christina M Marra
1From the *Department of Medicine, University of Washington, Seattle, WA; †Public Health-Seattle & King County HIV/STD Program, Seattle, WA; and Departments of ‡Neurology and §Epidemiology, University of Washington, Seattle, WA.
Abstract:
We reviewed 68 cases of possible neurosyphilis among 573 syphilis cases in King County, WA, from 3rd January 2012 to 30th September 2013; 7.9% (95% confidence interval, 5.8%-10.5%) had vision or hearing changes, and 3.5% (95% confidence interval, 2.2%-5.4%) had both symptoms and objective confirmation of complicated syphilis with either abnormal cerebrospinal fluid or an abnormal ophthalmologic examination.
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