Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

347
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
347
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

317
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
317
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

809
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
809
Aging01:26

Aging

1.0K
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
1.0K
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

316
In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
316
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

340
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
340

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A phase II randomized placebo-controlled study of fisetin to improve physical function in breast cancer survivors: the TROFFi study rationale and trial design.

Therapeutic advances in medical oncology·2026
Same author

Select Small Non-Coding RNAs Are Determinants of Survival in Older Adults.

Aging cell·2026
Same author

Menopausal Hormone Labels Should Rely on Evidence, Not Opinion.

JAMA·2026
Same author

Developing Topics.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

BDNF genotype and cognition in older adults with breast cancer and healthy controls in the Thinking and Living with Cancer Study.

Journal of geriatric oncology·2025
Same author

Accelerated biological aging and midlife frailty among U.S. military veterans.

The journals of gerontology. Series A, Biological sciences and medical sciences·2025
Same journal

An Electronic Health Record "Nudge" to Reduce Antipsychotic Medication Prescribing for Primary Care Patients With Dementia: A Pragmatic RCT.

Journal of the American Geriatrics Society·2026
Same journal

Reasons That Older Adults are Unable to Identify a Healthcare Agent.

Journal of the American Geriatrics Society·2026
Same journal

Assigning Probable Dementia Status Using Routinely Collected Electronic Health Record Data.

Journal of the American Geriatrics Society·2026
Same journal

Caregiver Burden at the Onset of Acute Hospital-At-Home.

Journal of the American Geriatrics Society·2026
Same journal

Utilization Patterns Among Heterogeneous Subgroups of Homebound Older Adults: A Latent Class Analysis.

Journal of the American Geriatrics Society·2026
Same journal

Off-Label Initiation of Gabapentin and Valproic Acid Among Long-Stay Nursing Home Residents With and Without Dementia.

Journal of the American Geriatrics Society·2026
See all related articles

Related Experiment Video

Updated: Mar 30, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.5K

Advancing Geriatrics Education Through a Faculty Development Program for Geriatrics-Oriented Clinician Educators.

Sandro O Pinheiro1,2, Heidi K White1,2, Gwendolen T Buhr1,2

  • 1Division of Geriatrics, Department of Medicine, School of Medicine, Duke University, Durham, North Carolina.

Journal of the American Geriatrics Society
|November 14, 2015
PubMed
Summary
This summary is machine-generated.

Faculty development programs enhance geriatric education. A Duke University mini-fellowship improved faculty self-efficacy in curriculum design and teaching, leading to better geriatrics training for physicians caring for older adults.

Keywords:
curriculum developmentfaculty developmentgeriatrics education

More Related Videos

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
07:21

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease

Published on: June 16, 2023

1.6K
Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum
04:36

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Published on: August 5, 2020

5.1K

Related Experiment Videos

Last Updated: Mar 30, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.5K
Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
07:21

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease

Published on: June 16, 2023

1.6K
Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum
04:36

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Published on: August 5, 2020

5.1K

Area of Science:

  • Medical Education
  • Geriatrics
  • Faculty Development

Background:

  • Growing population of older adults necessitates improved geriatric care.
  • Existing physician workforce requires enhanced training in geriatrics.
  • Need for skilled educators to develop and deliver geriatric curricula.

Purpose of the Study:

  • To assess the impact of a faculty development mini-fellowship program on educators' self-efficacy and teaching practices in geriatrics.
  • To improve the quality of geriatrics education delivered by faculty across various medical specialties.
  • To foster the development and implementation of new or revised geriatrics curricula in academic medical institutions.

Main Methods:

  • Duke University conducted a mini-fellowship program (2005-09) for 83 faculty from 52 institutions.
  • Program included workshops on curriculum development and teaching skills, followed by 1-year mentoring.
  • Assessment used pre/post self-efficacy surveys, program evaluations, and progress reports.

Main Results:

  • Significant gains (P < .001) in self-efficacy were observed at 1 week and 1 year post-program.
  • Largest gains reported in applying adult learning principles, writing learning objectives, and selecting instructional methods.
  • Participants demonstrated improved curriculum design skills and implemented new geriatrics curricula.

Conclusions:

  • The Duke mini-fellowship program effectively enhanced faculty self-efficacy in geriatric curriculum design and teaching.
  • The program contributed to improved geriatrics education within participants' home institutions.
  • This faculty development model is valuable for advancing geriatric medical education.