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Published on: August 16, 2021
The procurement landscape of pediatric tuberculosis treatment: a Global Drug Facility perspective
C Scott1, E Gardiner2, A de Lucia3
1The Global Alliance for TB Drug Development, New York, New York, USA.
Insights
New child-friendly tuberculosis (TB) drugs are available. Analysis of the Global Drug Facility
Area of Science:
- Global Health
- Pharmaceutical Policy
- Infectious Diseases
Background:
- Availability of child-friendly tuberculosis (TB) formulations is increasing.
- Global initiatives by organizations like the TB Alliance and World Health Organization (WHO) aim to improve pediatric TB treatment access.
- Understanding the market dynamics and distribution of pediatric TB drugs is crucial for effective delivery.
Purpose of the Study:
- To characterize the market and distribution pathways for pediatric TB drugs.
- To assess the functioning of the current market based on Global Drug Facility (GDF) data.
- To identify lessons learned and opportunities for future pediatric TB medicine delivery.
Main Methods:
- Analysis of Global Drug Facility (GDF) data on pediatric TB treatment delivery from 2007 to 2013.
- Contextualization of GDF data with WHO estimates of pediatric TB burden.
- Assessment of market functioning, lessons learned, and future opportunities.
Main Results:
- The Global Drug Facility (GDF) is a major procurer and supplier of pediatric TB medications globally.
- Between 2007 and 2013, GDF delivered over 580,000 pediatric TB treatments to more than 50 countries.
- The data provides insights into the current market landscape and GDF's role in supplying quality pediatric TB drugs.
Conclusions:
- The GDF plays a significant role in supplying pediatric TB treatments, particularly in high-burden countries.
- Analysis of GDF's experience offers valuable lessons for improving the delivery of current and future pediatric TB medicines.
- Further understanding of market dynamics is essential for optimizing pediatric TB drug access.
Abstract:
Simple, quality-assured, child-friendly formulations of existing first-line anti-tuberculosis (TB) drugs in the correct dosages are now becoming available. Efforts are currently underway by the TB Alliance, the World Health Organization (WHO), and its partners to make appropriate medicines available to treat children diagnosed with TB. The functioning of the current market and the distribution pathways in pediatric TB drugs now require characterization and understanding in order to develop appropriate strategies for delivery of these and other future pediatric TB medicines. The Stop TB Partnership's Global Drug Facility (GDF) plays a major role in supplying pediatric TB medications worldwide. GDF is considered to be the largest procurer of pediatric TB treatment and the largest supplier to national TB programs of quality pediatric drugs. Between 2007 and 2013, the GDF delivered more than 580, 000 treatments to children in over 50 countries, 14 of which are among the 22 high TB burden countries. We analyzed this data set in the context of WHO estimates of pediatric TB as well as other available information to assess the functioning of the current market, lessons learnt from the GDF experience in the market, and opportunities for future products.
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