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Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
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Pulmonary valve replacement and quality-of-life assessment
Flora H F Tsang1, Sophia J Wong2, Yiu-fai Cheung3
1Department of Cardiothoracic Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.
Asian Cardiovascular & Thoracic Annals
|November 17, 2015
Summary
Pulmonary valve replacement significantly improves quality of life in asymptomatic patients with chronic pulmonary regurgitation after tetralogy of Fallot repair. This procedure enhances both physical and mental wellbeing.
Area of Science:
- Cardiology
- Cardiac Surgery
- Quality of Life Research
Background:
- Chronic pulmonary regurgitation is a common complication following tetralogy of Fallot repair.
- Many patients with repaired tetralogy of Fallot remain asymptomatic despite pulmonary regurgitation.
- Health encompasses physical, mental, and social wellbeing, extending beyond disease absence.
Purpose of the Study:
- To investigate the impact of pulmonary valve replacement on the quality of life.
- Focus on asymptomatic patients with repaired tetralogy of Fallot and chronic pulmonary regurgitation.
Main Methods:
- Study included 25 asymptomatic patients (mean age 23.4 years) undergoing pulmonary valve replacement.
- Cardiac magnetic resonance imaging (MRI) was used for pre- and postoperative assessment.
- Quality of life was evaluated using the Chinese version of the SF-36v2 tool.
Main Results:
- Significant reductions in indexed right ventricular end-diastolic and end-systolic volumes post-surgery.
- All 8 domains of the SF-36v2 quality of life assessment showed improvement.
- Physical and mental component summary scores increased significantly after pulmonary valve replacement.
Conclusions:
- Pulmonary valve replacement is an effective intervention for improving quality of life.
- The procedure benefits patients with chronic asymptomatic pulmonary regurgitation post-tetralogy of Fallot repair.
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