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Phytochemistry of Daphne oleoides
Muhammad Riaz1, Asma Saleem1, Shabana Siddique1
1a Department of Chemistry , The University of Azad Jammu and Kashmir , Muzaffarabad , Pakistan.
Natural Product Research
|November 17, 2015
Summary
Daphne oleoides, a species in the Thymelaeaceae family, is a rich source of novel natural compounds with therapeutic potential. This review details its chemical constituents and pharmacological activities, highlighting its traditional medicinal uses.
Area of Science:
- Phytochemistry
- Pharmacology
- Ethnobotany
Background:
- The genus Daphne (Thymelaeaceae) comprises 70 species with a wide geographical distribution.
- Daphne oleoides, found in Pakistan, thrives in diverse climates, leading to novel chemical constituents.
- This species is recognized for its rich source of unique natural products with therapeutic properties.
Purpose of the Study:
- To review the chemical constituents isolated from Daphne oleoides.
- To summarize the pharmacological activities of these isolated compounds.
- To document the traditional medicinal uses of Daphne oleoides.
Main Methods:
- Literature review of chemical constituents from Daphne oleoides.
- Compilation of reported pharmacological activities.
- Analysis of ethnobotanical data on the species' use in folk medicine.
Main Results:
- Isolation of various natural molecules, including novel tris- and bis-coumarins, daphnane diterpenoids, and lignoids.
- Daphne oleoides exhibits a wide range of therapeutic properties, supported by modern research.
- The species has a history of use in herbal medicines for treating various ailments.
Conclusions:
- Daphne oleoides is a valuable source of chemically diverse and potentially therapeutic natural products.
- Further research into its compounds could lead to new drug discoveries.
- The traditional uses of Daphne oleoides are supported by its rich phytochemical profile.

