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Related Experiment Video

Updated: Mar 30, 2026

Surgical Correction for Pediatric Epiblepharon and Trichiasis
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Interventions for trachoma trichiasis.

Matthew Burton1, Esmael Habtamu, Derek Ho

  • 1International Centre for Eye Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, UK, WC1E 7HT.

The Cochrane Database of Systematic Reviews
|November 17, 2015
PubMed
Summary
This summary is machine-generated.

Trachomatous trichiasis surgery, particularly full-thickness tarsal plate incision and rotation, is effective in preventing lashes from touching the eye. Community-based delivery and various suture types yield comparable outcomes for this leading cause of infectious blindness.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Public Health

Background:

  • Trachoma is the primary infectious cause of blindness globally.
  • The World Health Organization (WHO) advocates the SAFE strategy (Surgery, Antibiotics, Facial cleanliness, Environmental hygiene) to combat trachoma.
  • This review updates previous analyses of interventions for trachomatous trichiasis.

Purpose of the Study:

  • To evaluate the effectiveness of interventions for treating trachomatous trichiasis in endemic populations.
  • To compare different surgical techniques, suture materials, and adjunctive treatments.

Main Methods:

  • Systematic review and meta-analysis of randomized controlled trials.
  • Searched multiple databases including CENTRAL, MEDLINE, and EMBASE up to May 2015.
  • Included 13 studies with 8586 participants, primarily from sub-Saharan Africa.

Main Results:

  • Full-thickness tarsal plate incision with rotation is the most effective surgical technique.
  • Bilamellar rotation outperformed unilamellar rotation; lid clamps reduced abnormalities; absorbable sutures were comparable to silk with fewer granulomas.
  • Epilation was less effective than surgery for mild trichiasis; peri-operative azithromycin showed imprecise effects on reducing post-operative trichiasis.

Conclusions:

  • Specific surgical techniques, like full-thickness tarsal plate incision and rotation, are effective in treating trachomatous trichiasis.
  • Community-based surgery and procedures by trained ophthalmic assistants are viable delivery models.
  • While not directly preventing blindness, interventions offer modest visual improvement and effective trichiasis elimination.