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Updated: Mar 30, 2026

Biomimetic Materials to Characterize Bacteria-host Interactions
Published on: November 16, 2015
Pathological-Condition-Driven Construction of Supramolecular Nanoassemblies for Bacterial Infection Detection
Li-Li Li1, Huai-Lei Ma1, Guo-Bin Qi2
1Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), No. 11 Beiyitiao, Zhongguancun, Beijing, 100190, China.
Abstract:
A pyropheophorbide-α-based building block (Ppa-PLGVRG-Van) can be used to construct self-aggregated superstructures in vivo for highly specific and sensitive diagnosis of bacterial infection by noninvasive photoacoustic tomography. This in vivo supramolecular chemistry approach opens a new avenue for efficient, rapid, and early-stage disease diagnosis with high sensitivity and specificity.
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