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Towards autonomous lab-on-a-chip devices for cell phone biosensing.

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Cell phones can be repurposed for chemical and biosensing using disposable lab-on-a-chip (LOC) devices. This approach leverages existing mobile ubiquity for widespread, accessible distributed biosensing applications.

Keywords:
Autonomous lab-on-a-chipCell phone biosensingPoint-of-care

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Area of Science:

  • Analytical Chemistry
  • Biotechnology
  • Mobile Technology

Background:

  • Modern cell phones possess untapped potential for chemical and biosensing applications.
  • Distributed biosensing requires accessible and ubiquitous platforms.

Purpose of the Study:

  • To review autonomous disposable lab-on-a-chip (LOC) devices for cell phone readout.
  • To examine cell phone resources critical for analytical detection.
  • To discuss universal architectures for unaccessorized phone compatibility.

Main Methods:

  • Review of autonomous disposable lab-on-a-chip (LOC) technologies.
  • Analysis of cell phone hardware and software capabilities for sensing.
  • Conceptualization of universal readout architectures.

Main Results:

  • Autonomous LOC devices can be designed to complement cell phone sensing capabilities.
  • Cell phone cameras, processors, and connectivity are key resources for biosensing.
  • Universal architectures can enable LOC readout on standard, unaccessorized phones.

Conclusions:

  • Repurposing cell phones with LOC devices offers a viable path for ubiquitous distributed biosensing.
  • This integration maintains the accessibility of mobile technology for analytical detection.
  • Future work should focus on developing standardized, universal LOC-phone interfaces.