Optical coherence tomography platforms and parameters for glaucoma diagnosis and progression

Area of Science:

• Ophthalmology
• Medical Imaging

Background:

• Optical coherence tomography (OCT) is crucial for diagnosing and monitoring ocular diseases like glaucoma.
• Initially, only the retinal nerve fiber layer was used; now, more structural parameters are available.
• OCT is also being explored for assessing ocular hemodynamics.

Purpose of the Study:

• To review spectral domain-optical coherence tomography (SDOCT) parameters for glaucoma assessment.
• To highlight advancements in structural and hemodynamic OCT parameters for glaucoma.

Main Methods:

• Review of current literature on SDOCT applications in glaucoma.
• Analysis of structural parameters (retinal nerve fiber layer, optic nerve head, macula).
• Evaluation of hemodynamic parameters derived from OCT (Doppler, angiography).

Main Results:

• New SDOCT parameters for retinal nerve fiber layer, optic nerve head, and macula show strong glaucoma diagnostic ability.
• Hemodynamic parameters from combined SDOCT and Doppler/angiography show promise for functional assessment in glaucoma.

Conclusions:

• OCT technology is evolving beyond structural assessment.
• SDOCT is becoming a multimodality tool for evaluating both structure and function in glaucoma.
• Advancements in OCT enhance understanding and clinical decision-making for glaucoma patients.