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Eicosanoids: a short review
1Department of Physiology, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, Republic of South Africa.
Journal of the South African Veterinary Association
|March 1, 1989
Abstract:
The biochemical reactions leading to the formation of eicosanoid compounds are reviewed. Arachidonic acid and similar homologous polyunsaturated acids are shown to be important precursors of these compounds. The partitioning of precursors between the cyclo-oxygenase and lipoxygenase enzyme systems leads to the prostanoid/thromboxane/prostacyclin and leukotriene families groups are reviewed. The mechanism of action of the prostacyclin group is briefly discussed.