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"Cold" Spondylodiscitis on 18F-FDG PET/CT in a Patient With Myelofibrosis
Etienne Rousseau1, Khun Visith Keu
1From the Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada.
Abstract:
A 74-year-old man was evaluated by bone scan for possible rib fractures, which revealed a diffuse skeletal uptake secondary to myelofibrosis and focal midthoracic uptake. Chest CT and F-FDG PET/CT demonstrated pathological vertebral fractures of the midthoracic spine, which appeared as a cold defect on PET comparing to intense marrow uptake related to myelofibrosis and a lung nodule with a low uptake, later biopsy-proven as non-small cell lung carcinoma (NSCLC). MRI confirmed CT findings for the spine noting also an enhanced epidural collection. Biopsies did not reveal malignant cells. Final diagnosis was spondylodiscitis and a stage I NSCLC.
