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Bone Scintigraphic Findings in MRSA Osteomyelitis
Patricia Cornejo1, Gerald A Mandell
1From the Phoenix Childrens Hospital, Phoenix, AZ.
Abstract:
Methicillin-resistant Staphylococcus aureus osteomyelitis is a severe form of infection characterized by multifocal or multiple segmental osseous involvement and subperiosteal abscess formation with increased frequency of extraosseous complications including pyomyositis, septic thrombus, and septic arthritis. Bone scan showed long segment and/or multifocal involvement in 4 of 5 patients with areas of abnormal increased and decreased uptake. The clinical presentations included limp and/or pain. Joint involvement was seen in 4 cases. Bone scan abnormalities correlated well with MRI findings of severe and extensive bone disease, abscess formation, muscle, as well as joint and soft tissue involvement.
Insights
Methicillin-resistant Staphylococcus aureus osteomyelitis presents with extensive bone and extraosseous involvement. Bone scans effectively detect these widespread infections, correlating with MRI findings.
Area of Science:
- Orthopedics
- Infectious Diseases
- Radiology
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) osteomyelitis is a severe bone infection.
- It often involves multiple bone segments and can lead to extraosseous complications.
Observation:
- This study examined 5 patients with MRSA osteomyelitis.
- Clinical symptoms included limp and pain.
- Joint involvement was observed in 4 cases.
Findings:
- Bone scans revealed multifocal or long-segment bone involvement in 4 patients.
- Abnormal uptake patterns (increased and decreased) were noted on bone scans.
- Bone scan findings correlated well with MRI, showing extensive bone disease and soft tissue involvement.
Implications:
- Bone scintigraphy is a valuable tool for assessing the extent of MRSA osteomyelitis.
- Accurate imaging is crucial for managing complex cases with potential for severe complications.
- Early detection and comprehensive imaging aid in treatment planning for MRSA bone infections.

