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Aspirin resistance and other aspirin-related concerns

Gaoyu Cai1, Weijun Zhou2, Ya Lu3

  • 1Department of Neurology and Institute of Neurology, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|November 18, 2015
PubMed

Insights

Aspirin is vital for cardiovascular disease prevention, reducing events and mortality. This review covers aspirin

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Aspirin is a cornerstone therapy for cardiovascular disease.
  • It effectively reduces ischemic events, recurrence, and mortality.
  • Concerns regarding aspirin resistance and adverse effects are increasing.

Purpose of the Study:

  • To review the historical context of aspirin's clinical use.
  • To discuss contemporary developments and challenges in aspirin therapy.

Main Methods:

  • Literature review of historical and recent studies on aspirin.
  • Analysis of clinical data regarding aspirin efficacy and resistance.

Main Results:

  • Aspirin significantly improves long-term prognosis for cardiovascular patients.
  • A growing body of literature addresses aspirin resistance.
  • Some patients experience adverse reactions to aspirin.

Conclusions:

  • Aspirin remains crucial in cardiovascular disease management.
  • Understanding aspirin resistance and adverse effects is vital for optimizing patient outcomes.

Keywords:
Adverse effectsAspirinClinical useResistance phenomenon

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